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Omni-Biotic AB 10
"Effect of a Multispecies Probiotic on Intestinal and Skin Colonization by Multidrug Resistant Gram Negative Bacteria in Patients in a Long Term Care Facility"
Year Published: 2020
Study Type: pilot study
Related Omni-Biotic Formulation: AB 10
Elderly long term care facility patients colonized with multidrug resistance gram negative bacteria were treated with Omnio-Biotic AB 10 (AAD) for twelve weeks. Colonization was eliminated in 58% of patients at 8-20 weeks following intervention.
"Probiotics Use for Antibiotic Associated Diarrhea: A Pragmatic Participatory Evalution in Nursing Homes"
Year Published: 2020
Study Type: participatory evaluation
Related Omni-Biotic Formulation: AB 10
Omni-Biotic AB 10 (AAD) was administered to residents receiving antibiotics at three nursing homes. Compared to a control group receiving antibiotics without probiotic supplementation, the AB 10 group demonstrated significantly fewer episodes of antibiotic associated diarrhea.
"Probiotics in Clostridium difficile infection: reviewing the need for a multistrain probiotic"
Year Published: 2013
Study Type: retrospective review
Related Omni-Biotic Formulation: AB 10
This retrospective chart review of ten CDI patients for whom recurrence was expected found that all patients on adjunctive Omni-Biotic AB 10 (AAD) therapy showed complete clinical resolution.
"Use of a multi-species probiotic for the prevention of antibiotic associated diarrhea"
Year Published: 2010
Study Type: observational study
Related Omni-Biotic Formulation: AB 10
This observational study demonstrated the successful use of Omni-Biotic AB 10 (AAD) for primary prevention of antibiotic associated diarrhea in post surgical patients.
"Probiotics for the prevention of antibiotic-associated diarrhea and Clostridium difficile infection among hospitalized patients: systematic review and meta-analysis"
Year Published: 2013
Study Type: review article
Related Omni-Biotic Formulation: AB 10
This systematic review and meta-analysis evaluated the efficacy of co-administration of probiotics with antibiotics. Findings demonstrated that probiotics used concurrently with antibiotics reduce the risk of antibiotic associated diarrhea and C. difficile infection.
Omni-Biotic Stress Release
"Influence of 4-week multi-strain probiotic administration on resting state functional connectivity in healthy volunteers"
Year Published: 2019
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: Stress Release
Functional brain connectivity changes were observed in the default mode network, salience network, and middle and superior frontal gyrus network among three groups randomly assigned to receive a probiotic formulation, a placebo, or nothing at all (controls). The Omni-Biotic Stress Release probiotic group showed a significant increase in salience network activity (associated with increased attention, perception, cognition) and significant decrease in default mode network and MFGN activity (associated with reduced distraction and improved reasoning, decision-making, learning, and creativity).
"Probiotics drive gut microbiome triggering emotional brain signatures"
Year Published: 2018
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: Stress Release
Behavioral analysis was performed on individuals randomized to three groups, those receiving a probiotic formulation, a placebo, or nothing at all (controls). The Omni-Biotic Stress Release probiotic group showed a significant increase in positive mental disposition as well as decreased vulnerability to depression, hopelessness, and risk aversion. The probiotic group also demonstrated more stable decision making and recall when challenged with unpleasant stimuli.
"Effects of an oral synbiotic on the gastrointestinal immune system and microbiota in patients with diarrhea-predominant irritable bowel syndrome"
Year Published: 2019
Study Type: observational trial
Related Omni-Biotic Formulation: Stress Release
Symptomatic IBS-D patients were given a 4-week regimen of the Omni-Biotic Stress Release probiotic formulation. Analysis before and after the probiotic regimen demonstrated increases in microbiota diversity and nourishing short chain fatty acid production as well as reduced colonic CD4+ T cells (immune cells which are increased in IBS) and fecal zonulin (protein associated with intestinal hyperpermeability/leaky gut). Participants also reported a reduction in IBS symptom severity.
"The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems"
Year Published: 2015
Study Type: review article
Related Omni-Biotic Formulation: Stress Release
This review summarizes the available evidence describing the bi-directional gut-brain relationship including neural, endocrine, immune, and humoral pathways. It also explores relevant pathophysiological mechanisms.
"Stress and the Microbiota–Gut–Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome"
Year Published: 2015
Study Type: review article
Related Omni-Biotic Formulation: Stress Release
This review highlights the evidence supporting the connection between stress and the gut microbiota, with specific focus on the mechanisms by which the microbiota impacts stress response, behavior, and visceral pain.
Omni-Biotic Balance
"Homeostatic Immunity and the Microbiota"
Year Published: 2017
Study Type: review article
Related Omni-Biotic Formulation: Balance
This review explores the roles the microbiome plays in the development and function of the immune system.
"Role of the Microbiota in Immunity and Inflammation"
Year Published: 2014
Study Type: review article
Related Omni-Biotic Formulation: Balance
This review discusses the relationship between the gut microbiome and immunity highlighting the influence of modern diet, pharmaceuticals and hygiene on rising rates of inflammatory and autoimmune disorders.
Omni-Biotic Hetox
"Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis"
Year Published: 2016
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: Hetox
Stable cirrhotic patients received Omni-Biotic Hetox or placebo for 6 months and were followed for an additional 6 months. The probiotic group demonstrated increased liver function.
"Effects of a multi-strain probiotic supplement for 12 weeks in circulating endotoxin levels and cardiometabolic profiles of medication naïve T2DM patients: a randomized clinical trial"
Year Published: 2017
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: Hetox
Adult TD2M patients were treated with Omni-Biotic Hetox (Barrier) or placebo. The probiotic intervention group demonstrated significant improvement in waist-hip ratio and HOMA-IR (insulin resistance).
"Effects of a 6-month multi-strain probiotics supplementation in endotoxemic, inflammatory and cardiometabolic status of T2DM patients: A randomized, double-blind, placebo-controlled trial"
Year Published: 2018
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: Hetox
Adult TD2M patients were treated with Omni-Biotic Hetox (Barrier) or placebo. The probiotic intervention group demonstrated significantly decreased levels of endotoxin, glucose, insulin resistance, triglycerides, total cholesterol and total/HDL-cholesterol ratio compared to the placebo group.
"The gut-liver axis and the intersection with the microbiome"
Year Published: 2018
Study Type: review article
Related Omni-Biotic Formulation: Hetox
This review discusses gut-liver communications in various forms of liver disease and the potential to use the microbiome to determine the stage of liver disease as well as predicting the effects of dietary and pharmaceutical interventions.
Omni-Biotic Panda
"Identification of Strong Interleukin-10 Inducing Lactic Acid Bacteria which Down-Regulate T Helper Type 2 Cytokines"
Year Published: 2005
Study Type: preclinical analysis
Related Omni-Biotic Formulation: PandA
This study identified the ability of Omni-Biotic PandA to modulate the production of inflammation influencing cytokines and divert the immune system in a regulatory or tolerant mode.
"Selection of Probiotic Bacteria for Prevention of Allergic Diseases: Immunomodulation of Neonatal Dendritic Cells"
Year Published: 2007
Study Type: preclinical analysis
Related Omni-Biotic Formulation: PandA
This study identified the ability of Omni-Biotic PandA to influence immune cell maturation.
"The Effects of Selected Probiotic Strains on the Development of Eczema (the PandA study)"
Year Published: 2009
Study Type: double blind, randomized controlled trial
Related Omni-Biotic Formulation: PandA
Omni-Biotic PandA or a placebo was administered prenatally and for the first year of life to infants genetically predisposed to allergic disease. The probiotic intervention group demonstrated significantly lower risk/incidence of allergic disease/atopic dermatitis through the 2 year study period.
"Probiotic Supplementation Influences Faecal Short Chain Fatty Acids in Infants at High Rick for Eczema"
Year Published: 2015
Study Type: double blind, randomized controlled trial: follow-on
Related Omni-Biotic Formulation: PandA
Omni-Biotic PandA or a placebo was administered prenatally and for the first year of life to infants genetically predisposed to allergic disease. Infant fecal analyses demonstrated higher levels of beneficial short chain fatty acids and lactate in the probiotic intervention group.
"Probiotics and Primary Prevention of Atopic Dermatitis: A Meta-Analysis of Randomized Controlled Studies"
Year Published: 2014
Study Type: review article
Related Omni-Biotic Formulation: PandA
This meta analysis found that probiotics have a protective role in atopic dermatitis (eczema) prevention when administered during the pre- and post-natal period.
