Gut-Maternal/Neonatal

Shifts in the maternal microbiome and immune function occur naturally during the course of pregnancy. However these changes can negatively impact fetal immune and microbiome development. This in turn can increase the potential risk of allergic and autoimmune conditions in later life.

Clinical studies have demonstrated the immune development and microbiome balancing power of OMNi-BiOTiC® PandA with outcomes including reduced risk of infant/childhood allergic and atopic disease (i.e. eczema), reduced colic, and improved maternal gut function and comfort.

"Identification of Strong Interleukin-10 Inducing Lactic Acid Bacteria which Down-Regulate T Helper Type 2 Cytokines"

Year Published: 2005

Study Type: preclinical analysis

Related Omni-Biotic Formulation: PandA

This study identified the ability of Omni-Biotic PandA to modulate the production of inflammation influencing cytokines and divert the immune system in a regulatory or tolerant mode.

"Selection of Probiotic Bacteria for Prevention of Allergic Diseases: Immunomodulation of Neonatal Dendritic Cells"

Year Published: 2007

Study Type: preclinical analysis

Related Omni-Biotic Formulation: PandA

This study identified the ability of Omni-Biotic PandA to influence immune cell maturation.

"The Effects of Selected Probiotic Strains on the Development of Eczema (the PandA study)"

Year Published: 2009

Study Type: double blind, randomized controlled trial

Related Omni-Biotic Formulation: PandA

Omni-Biotic PandA or a placebo was administered prenatally and for the first year of life to infants genetically predisposed to allergic disease. The probiotic intervention group demonstrated significantly lower risk/incidence of allergic disease/atopic dermatitis through the 2 year study period.

"Probiotic Supplementation Influences Faecal Short Chain Fatty Acids in Infants at High Rick for Eczema"

Year Published: 2015

Study Type: double blind, randomized controlled trial: follow-on

Related Omni-Biotic Formulation: PandA

Omni-Biotic PandA or a placebo was administered prenatally and for the first year of life to infants genetically predisposed to allergic disease. Infant fecal analyses demonstrated higher levels of beneficial short chain fatty acids and lactate in the probiotic intervention group.

"Probiotics and Primary Prevention of Atopic Dermatitis: A Meta-Analysis of Randomized Controlled Studies"

Year Published: 2014

Study Type: review article

Related Omni-Biotic Formulation: PandA

This meta analysis found that probiotics have a protective role in atopic dermatitis (eczema) prevention when administered during the pre- and post-natal period.

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